作者：赵梦雅,张美云,杨　强,聂景怡,解宏滨,宋顺喜,鲁　鹏
刊发：中国造纸学报,2019,34(4):1-6
 

基金项目:国家重点研发计划（2017YFB0308300）；广西清洁化制浆造纸与污染控制重点实验室开放基金资助（KF201701）；陕西省重点研发计划（2017GY-140）；陕西省重点科技创新团队计划（2017KCT-02）。
 

中文关键词:  微晶纤维素  金属有机框架化合物  复合材料  抗菌
Key Words:microcrystalline cellulose  metal-organic frameworks  composites material  antibacterial
 

中文摘要:     
采用原位沉积法将两种金属有机框架化合物（Metal-Organic Frameworks，MOFs）MOF-5和1，3，5-均苯三甲酸铜（Ⅱ）（HKUST-1）负载在微晶纤维素（MCC）上，制备出MCC/MOF-5和MCC/HKUST-1二元复合材料以及MCC/MOF-5/HKUST-1和MCC/HKUST- 1/MOF-5三元复合材料；分别采用傅里叶变换红外光谱仪（FT-IR）、X射线衍射仪（XRD）及扫描电子显微镜（SEM）分析复合材料的化学组成和微观形貌；以大肠杆菌（Escherichia coli， E-coli）为测试菌种，通过测定抑菌圈直径检测复合材料的抗菌性能。结果表明，实验成功制备出了表面覆盖有立方体结构的MOF-5和棒状结构的HKUST-1的二元和三元复合材料；由于金属离子的协同抗菌作用，三元复合材料较二元复合材料对大肠杆菌具有更优异的抗菌性能；由于Zn2+的抗菌能力大于Cu2+，MCC/HKUST-1/MOF-5的抗菌效果较MCC/MOF-5/HKUST-1好。
 

Abstract:     
Binary composites (MCC/MOF-5 and MCC/HKUST-1) and ternary composites (MCC/MOF-5/HKUST-1 and MCC/HKUST-1/MOF-5) were prepared by in-situ deposition of metal-organic frameworks (MOF-5 and HKUST-1) onto the surface of microcrystalline cellulose (MCC). FT-IR and XRD were used to characterize the chemical structures of the composites. The morphologies of the composites were observed by SEM. Escherichia coli (E. coli) was used as a test strain to evaluate the antibacterial ability by measuring the diameter of the inhibition zone. The results showed that the binary and ternary composites were successfully prepared. MOF-5 and HKUST-1 on the surface of MCC exhibited cubic and rod-like shape respectively. Due to the synergistic antibacterial effect of metal ions, the ternary composites had better antibacterial properties against E. coli than the binary composites. The antibacterial effect of MCC/HKUST 1/MOF-5 was better than that of MCC/MOF-5/HKUST-1 as the antibacterial capacity of Zn2+ was greater than Cu2+.